Skip Navigation


British Medical Bulletin Advance Access originally published online on May 29, 2008
British Medical Bulletin 2008 86(1):59-75; doi:10.1093/bmb/ldn018
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
86/1/59    most recent
ldn018v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Matyka, K. A.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matyka, K. A.
Related Collections
Right arrow Diabetes
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2008. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Type 2 diabetes in childhood: epidemiological and clinical aspects

K. A. Matyka

Warwick Medical School, Clinical Sciences Research Institute, University Hospital Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry CV2 2DX, UK

Correspondence to: K. A. Matyka Clinical Sciences Research Institute University Hospital Coventry and Warwickshire NHS Trust Clifford Bridge Road Coventry CV2 2DX UK. E-mail: k.a.matyka{at}warwick.ac.uk

Background: The global obesity epidemic has raised concerns about the risk of a tide of Type 2 diabetes (T2DM) in childhood. This paper aims to review the recent data on the epidemiology of this problem as well as the clinical concerns.

Sources of data: A literature search was performed on Medline, and articles about childhood T2DM, in English and published from 2000 to 2008, were reviewed.

Areas of agreement: A review of 16 paediatric studies suggest that although T2DM is now more widely reported in childhood, the numbers are still reasonably small although the data do suggest that ethnicity is an important risk factor.

Areas of controversy: Although there are emerging data on what appears to be a significant risk of both microvascular and macrovascular complications in youth onset T2DM, the most appropriate management remains unclear. Currently, adult guidelines for management of T2DM are being extrapolated to the adolescent population with T2DM.

Growing points: Studies are currently underway to examine the pharmacological management of childhood T2DM.

Areas timely for developing research: More data are necessary on the exact prevalence of T2DM among a variety of populations to provide a greater understanding of the risk factors for T2DM and provide indications for screening. In the meantime, great emphasis needs to be placed on obesity prevention if we are to protect the health of future generations of children.

Keywords: child • type 2 diabetes

Accepted for publication April 18, 2008.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.